Best Joint Supplements in 2022 | Our Top 3 Picks

Best Joint Supplements Currently on The Market

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Searching for the best joint supplement to combat joint pain & stiffness and enhance your quality of life?

When most of us think of supplements, multivitamins or protein powders are usually the first that come to mind. Don’t get us wrong, these products could be beneficial to your diet and lifestyle.

However, people usually only start caring for joint health supplements after the major problems start popping up; such as chronic joint pain and loss of mobility.

If this is you and you’re researching the most effective joint formulas on the market, you’ve landed in the right place. Our team has consulted nutritionists and experts to see what you should aim for (in terms of natural ingredients) when making your choice.

So, let’s see which supplements we’ve chosen as the safest and most effective natural options to protect your joints long-term.

What Are Joint Supplements and How Do They Work?

Generally speaking, joint supplements contain ingredients that are linked to increased joint protection and improved ease of movement. Joint supplements are used by people from all backgrounds and lifestyles – from office workers, young athletes, to the older folks wanting to protect optimal joint health and function.

The efficacy of each supplement is different and depends on its ingredient formula. If a product contains scientifically-backed ingredients, then it’ll be worth considering. If it only contains pointless fillers and underresearched compounds then it will be a waste of your time and money. Sometimes, a low-quality joint supplement can also lead to negative side effects.

Luckily, we’ve conducted all the research today and only recommended what we believe are the best options that are available currently on the market.

What are the Benefits of Joint Supplements? 

Joint supplements work to give you benefits such as;

  • Protection of your joints
  • Reduction in pains and aches
  • Improved joint lubrication
  • Cartilage protection and repair
  • Managing symptoms of arthritis

Each joint supplement will work slightly differently for you, depending on which ingredients it contains in its formula. For instance, Glucosamine offers a wide range of benefits including reducing joint pain and improving joint motility (and more), so you’ll experience these if the joint product you take uses Glucosamine.

Best Ingredients in Joint Supplements 

There are always 4 core ingredients that we look for in a high-quality joint supplement: Turmeric, MSM, Glucosamine, and Chondroitin.

The aforementioned ingredients are the most clinically evidenced you can find currently on the market to support optimal joint function.

Not only that, some of these ingredients are shown in numerous clinical studies to work especially well when taken together – such as Glucosamine+Chondroitin.

By searching for specific ingredients when looking for the best joint supplement online, you’ll quickly see which companies have put in the effort in their research and formulation of the supplement, and which companies are skimping on their ingredients.

Can Joint Supplements Cause Side Effects?

Before taking any supplement, it’s a smart idea to check if it’s safe for you or not.

The good news is that most natural joint supplements on sale today contain safe ingredients, in safe dosages. Our favorite ingredients, such as Glucosamine and Chondroitin, aren’t shown to cause any major adverse effects in clinical studies. They remain some of the safest ingredients to ingest.

The most important part is to check if the ingredients in a joint supplement are natural. If the formula is 100% natural and dosed correctly, it will be highly unlikely to cause you any side effects. On the other hand, chemicals or drugs obtained from questionable sources may cause negative reactions.

One easy way to know if a supplement you’re purchasing has passed the quality and safety criteria is by checking if it is manufactured in cGMP and FDA-registered facilities.

In the past year alone, we’ve analyzed and inspected over 30 joint supplements, comparing them against each other to see which offers the most value. The result of our research has enabled us to present to you the top 3 best joint health supplements on offer right now.

Best Joint Supplements 2022

1. Physio Flex Pro

Physio Flex Pro

Physio Flex Pro is a state-of-the-art joint supplement created by SRS Nutra, an innovative brand that’s been gaining a lot of attention (in fact, it’s becoming difficult to avoid the positive reviews!).

Physio Flex Pro ticked all of our boxes in terms of the ingredients we were looking for. These included Glucosamine, Chondroitin Sulfate, MSM, Turmeric, and BioPerine.

In total, Physio Flex Pro contains 8 clinically-backed ingredients overall that work together, ensuring that you get what you pay for with no production costs being spared by SRS Nutra. 

Physio Flex Pro is also personally endorsed by physiotherapists around the world, including respected Dr. Kavita who specializes in musculoskeletal and orthopedic conditions – so you can rest assured that Physio Flex Pro is the real deal.


  • 8 natural ingredients clinically proven to combat joint pain, improve mobility, and repair cartilage
  • Effective at reducing joint inflammation
  • Clean & safe ingredient formula
  • Manufactured in the USA, in the golden standard cGMP-registered & FDA-approved facilities


Physio Flex Pro Ingredients: 

Physio Flex Pro Ingredients

The formula of Physio Flex Pro is what captured our attention originally; it contains by far the most effective combination of ingredients we’ve seen on the market to enhance joint health.

Not only is the quality of ingredients superior, but Physio Flex Pro also contains the most ingredients out of all the best joint health supplements we’ve ranked on offer today.

Here’s a closer look at the 8 ingredients in Physio Flex Pro:

  • Glucosamine: A naturally occurring compound that’s been shown to alleviate joint pain and increase motility in numerous clinical trials.
  • Chondroitin Sulfate: Research shows that Chondroitin works in synergy with Glucosamine to provide substantial joint protection. 
  • Turmeric Extract: Contains high amounts of the antioxidant curcumin that is the most researched natural anti-inflammatory compound. It is proven to relieve joint aches and improve range of movement.
  • MSM (methylsulfonylmethane): In addition to increasing joint flexibility and lowering inflammation on a cellular level, MSM has been shown to improve the repair of connective tissues, ensuring optimal long-term joint health.
  • Bromelain: Naturally found in pineapples, Bromelain is a powerful anti-inflammatory enzyme that is shown to protect joint cartilage as well as improve the digestion of other nutrients in the formula.
  • Ginger Extract: Another strong antioxidant with anti-inflammatory qualities that is known to reduce joint stiffness, among myriad other studied health benefits.
  • Bioperine: A patented extract of black pepper that works to enhance nutrient absorption, effectively boosting the overall effectiveness of Physio Flex Pro as a whole.

Customer Reviews: 

We’re yet to come across a negative review of Physio Flex Pro on the internet. Users report that the product is delivered on time and worked as claimed by improving their quality of life and by easing their range of motion and reducing joint pain.

As mentioned, Physio Flex Pro is also recommended by Dr. Kavita, a world-renown doctor who specializes in Orthopedic & musculoskeletal recovery.

For the price of $2.06 per daily serving, we’re inclined to agree with other reviews. While it’s not the cheapest product, Physio Flex Pro is worth the investment if you’re able to afford it.

Interested in Physio Flex Pro?

-Click Here to Get Prices-

2. Performance Lab Flex

Performance Lab Flex

Performance Lab Flex is another premium joint care supplement. While it’s number two on our list, Performance Lab Flex is by no means inferior. As a matter of fact, Performance Lab Flex contains one of the cleanest-quality formulas we’ve seen in any joint supplement.

This is the key selling point of the Performance Lab brand – producing the highest-quality formulas using in-house, patented nutrition technology. When it comes to production quality, Performance Lab Flex is second to none.

In terms of benefits, Performance Lab Flex works to help you with:

  • Connective tissue lubrication and shock absorption
  • Combating joint aches and inflammation
  • Rapid recovery after exercise
  • Strengthening of ligaments and tendons
  • Improving flexibility
  • Supporting joint health in the long-term


  • 6 patented ingredients
  • Supports all aspects of joint health & function
  • Provides shock & impact absorption
  • Long-term connective tissue protection
  • Save when buying in bulk


  • More expensive than competitors – $2.3 per daily serving
  • Only sells from

Performance Lab Flex’s Ingredients

Each serving of Performance Lab Flex provides you with a unique stack of 100% natural ingredients – all clinically supported to reduce joint inflammation, increase flexibility, and protect joint function as you get older. There is no unnecessary fluff or fillers inside Performance Lab Flex – only “the cream of the crop”.

The ingredients in Performance Lab Flex include:

Performance Lab Flex Ingredients

In case that label image didn’t load properly for you, here is an ingredient list in Performance Lab Flex:

  • AprèsFlex® Boswellia Serrata
  • CurcuWIN® Curcumin, 250 mg
  • Glucosamine Sulfate 2KCI
  • Mythocondro® Chondroitin Sulfate
  • OptiMSM® Methylsulfonylmethane (MSM)
  • NutriGenesis® Strontium

As you probably noticed, each ingredient of Performance Lab Flex comes in its purest, most potent, and most bioavailable version. Everything is inside vegan, prebiotic-infused capsules for optimal digestion & absorption.

Obviously, putting so many high-quality patented ingredients rises the production cost for the manufacturer, subsequently rising the price of Performance Lab Flex. That said, we think Performance Lab Flex’s tried and tested formula with real benefits is well worth the money.

Customer Reviews: 

Much like all the other products on this list, Performance Lab Flex boasts glowing online reviews. Many customers say it has helped them with the ease of movement and reduced joint stiffness and pain which plagued them for years beforehand.

We haven’t found any reports of side effects, and we don’t think any will emerge. Why? Because the formula is top-of-the-line quality and uses standardized doses of its key ingredients – making it extremely safe and effective.

Interested in Performance Lab Flex?

-Click Here to Get Prices-

3. ProJoint Plus

Coming in third on our list is ProJoint Plus.  

ProJoint Plus

ProJoint Plus contains great ingredients, ticking most of the boxes for us; it has MSM, chondroitin, turmeric, and glucosamine.

Taking 3 capsules a day with food, or up to 6 capsules per day for the first two weeks for quicker relief, should give you noticeable effects in terms of pain reduction and other arthritis symptoms.

While the ingredients themselves are great, it’s always vital to look at their dosages as well. ProJoint Plus contains a bit less MSM than we’d want at 25mg per serving. For comparison, our number one supplement on the list offers 100mg of MSM.

With that said, ProJoint Plus is still far better than most joint supplements out there. It is also the least expensive option on this list. A 15-day supply bottle of ProJoint Plus costs $29.95, and a 2-bottle option (which lasts 30 days) will set you back by $52.95.


  • Some highly effective ingredients in its formula 
  • Excellent customer reviews
  • Helps to diminish joint pain & inflammation


  • Low dosage of some ingredients, mainly MSM
  • Only 20 servings per container (less than 1 months supply)

Ingredients in ProJoint Plus

ProJoint Plus contains some excellent ingredients for a joint supplement. These include:

  • Glucosamine Sulfate – 1500mg
  • Boswellia Extract – 200mg
  • Chondroitin Sulfate – 150mg
  • Turmeric (150mg)
  • Quercetin (25mg)
  • Methionine (25mg)
  • MSM (25mg)
  • Bromelain (25mg)
ProJoint Plus Supplement

As we said, the dosages of some of these could be higher for a more potent effect. But, for the money, it is still a thumbs up from us.

Customer Reviews

All things considered, ProJoint Plus is a solid formula – most customer reviews confirm it. If you aren’t able to afford the more expensive options on this list, ProJoint Plus should still be enough to provide you with a noticeable relief from joint stiffness and pain, amongst others.

Interested in ProJoint Plus?

-Click Here to Get Prices-


Hopefully, our best joint supplements guide has driven home the importance of making the right choice (and doing enough research to do so).

Our pick of the year is Physio Flex Pro, which offers clinically effective ingredients at potent dosages for quick relief, and the price is good for the quality you’re getting, as well (with some excellent deals when you buy multiple bottles).

Performance Lab Flex is another excellent option due to its high-quality, effective formula with patented ingredients. It is more focused on athletes and people who exercise often to promote joint protection and recovery.

However, generally speaking, all of the products on this list can deliver the benefits that they promise, so you can’t really go wrong with any of them.

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