Instaflex Advanced Review: Does it Work? (Jan. 2023)

Instaflex Review

Here’s our Instaflex Advanced report. Our team is going to analyze this supplement to see how it compares to other joint stacks on the market in terms of reducing joint pain, promoting flexibility, and protecting long-range joint function as you get older.

The Pros

  • Contains a high-quality turmeric extract
  • Uses patented Boswellia serrata extract
  • Decent effects on joint pain and overall joint health

The Cons

  • Taking collagen orally does not increase collagen production
  • Hyaluronic acid is severely underdosed
  • Resveratrol has no proven effects on joints
  • Missing core ingredients such as MSM

Instaflex Advanced Analysis Summary

Instaflex Advanced (or simply Instaflex) isn’t a bad joint health supplement. It consists of natural active ingredients which makes it ideal for people who’re looking for some joint support as they get older. But Instaflex Advanced comes with some major downsides; pointless ingredients, tiny and ineffective dosages, and some key missing compounds. The serving size is small, and the price – quite high! Instaflex will give you some benefit, but in terms of value for money, there are definitely better joint stacks available on the market today.

About Instaflex Advanced

Instaflex Advanced, or just Instaflex, is one of the most popular joint supplements on sale today. It has been one of the leading joint stacks for some time now, and it doesn’t look like it’s going to be forgotten anytime soon.

Instaflex comes in different versions, including Instaflex Advanced cream, which is used for topical application and short-term pain relief.

So, why is there so much hype around Instaflex? What does this product do? Who is it for?

According to the manufacturer, Instaflex Advanced is a natural anti-inflammatory supplement. It’s designed to relieve discomfort and pain in your joints. In addition, Instaflex helps improve mobility of your joints, helping you to have a wider range of motion without experiencing pain.

The most impressive claim of all, however, is that Instaflex will give you joint pain relief within 7 days.

It is to be expected of joint supplements to promise improved joint flexibility and pain reduction. That is what they’re made for!

But very few joint products will provide substantial relief in 7 days! The best joint stacks usually need to be taken for many weeks to see benefits, and over time, these benefits accumulate and become more noticeable.

So, does Instaflex Advanced really work as claimed? Or is the 7-day promise just a marketing trick?

Is Instaflex Advanced safe? Is it a good value for money? What is inside Instaflex Advanced? How does it compare to other joint supplements on sale right now? We share our thoughts in our full Instaflex Advanced review below.

Benefits of Instaflex Advanced

  • Relieves joint pain
  • Improves daily comfort
  • Increases flexibility
  • Promotes long-term joint function

Who Makes Instaflex Advanced?

Instaflex Advanced is made by Adaptive Health LLC, a U.S. supplement company.

Adaptive Health was founded in 2009. It was that year that Instaflex Original was launched. The product was a huge success, which prompted the manufacturers to come up with Instaflex Advanced – the one we’re reviewing today.

Due to their success, the Adaptive Health team have expanded into 3 different offices in North America. Their office locations are the following:

  • Bethesda: 6710A Rockledge Drive Suite 500, Bethesda, MD 20817
  • Charlotte: 615 S College St Ste 1300, Charlotte, NC 28202
  • Boston: 116 Huntington Ave, Boston, MA 02116

If you are looking to contact Instaflex’s manufacturers regarding their products, their email is: [email protected]

How to Use Instaflex Advanced (Dosage Instructions)

Using Instaflex Advanced is simple. You should take 1 capsule per day with water, at any time of the day. The most important thing is to be consistent with using Instaflex Advanced, in order to get the most out of the product.

Ingredients in Instaflex Advanced

Here are the ingredients in Instaflex Advanced:

  • Turmeric (200mg)
  • Resveratrol (100mg)
  • ApresFlex Boswellia serrata extract (100mg)
  • UCII (25% collagen) (40mg)
  • Hyaluronic acid (5mg)
  • BioPerine (5mg)
Instaflex Advanced Ingredient Label & Information

We’re happy that there are no proprietary blends in Instaflex Advanced. Seeing the ingredient doses allows us to check if they are safe and effective. In terms of formula as a whole, it looks good, although there are some issues that we’ll address below.

We’ll begin by inspecting each Instaflex Advanced ingredient individually. With each one, we’ll tell you what the scientific research says, whether the ingredient belongs to a joint health supplement, and if it is dosed correctly. Afterwards, we’ll share our thoughts on the Instaflex Advanced formula as a whole.

1. Turmeric (95% curcuminoids) – 200mg

Turmeric’s active compounds, curcuminoids, can have a major impact on your joint pain, flexibility, and overall health. Curcuminoids are anti-inflammatory by nature, which means they can help with your joint pain and joint degeneration if the root cause is inflammation.

Curcumin has a few additional joint health-supportive qualities. It enhances collagen production, reduces free radical damage, and fights glycation end-products that damage connective tissues. Instaflex Advanced has 200mg of high-curcuminoid turmeric, which is a good dosage.

2. Resveratrol – 100mg

Resveratrol is a strong antioxidant. It lowers oxidative stress caused by free radicals, which can damage your body over time.

Studies show that resveratrol may have beneficial effects on cholesterol, cardiovascular health, and even lifespan.

However, most of the evidence on resveratrol comes from a petri dish or animal studies. At the moment, there is no solid human evidence that 100mg of resveratrol will do anything for your joint health or function.

3. Boswellia serrata extract – 100mg

Boswellia serrata is one of the most effective natural remedies for long-term joint health. It contains boswellic acids which inhibit the enzyme called 5-LOX. This enzyme is involved in destroying your joints’ connective tissues.

By blocking this enzyme, boswellic acids help to protect your joints from age-related wear and tear. Instaflex Advanced contains 100mg of the patented ApresFlex Boswellia, which is more than enough to see benefits! (source:

4. UCII (25% collagen) – 40mg

We don’t know why manufacturers keep using collagen in joint supplements. It might look attractive on a label to the layperson, but consuming collagen orally will not increase actual collagen production within your joints or other tissues.

Regardless of which type of collagen it is – chicken collagen, type II collagen, or anything else – it’s all ineffective. Contrary to the popular belief, this is a completely unproven ingredient in Instaflex Advanced. A big waste of capsule space that doesn’t have any benefit whatsoever.

5. Hyaluronic acid (89%) – 5mg

Hyaluronic acid can be an effective joint health enhancer. It seems to work particularly well are reducing joint pain. Studies show that people suffering from osteoarthritis experience less joint pain from taking 80-200mg of hyaluronic acid per day.

The issue is that, as you can see, Instaflex Advanced only has 5mg of the active ingredient. The human studies that showed any benefits used more than 16 times the amount in Instaflex.

6. BioPerine – 5mg

BioPerine is a patented name for black pepper extract. The active compounds in black pepper, in higher amounts, boost the bioavailability of other ingredients.

BioPerine is particularly useful in products like Instaflex Advanced which has turmeric. This is due to the fact that turmeric doesn’t absorb very well unless you take it alongside black pepper extract.

Our Commentary on Instaflex Advanced Formula

All things considered, Instaflex Advanced is not a bad joint supplement at all. It is more effective than a lot of popular joint stacks on the market right now. But it’s also far from the very best.

Instaflex contains a few great ingredients. We get some high-curcuminoid turmeric powder, some quality Boswellia Serrata extract, and a bit of hyaluronic acid.

These supplements have synergistic benefits on flexibility, joint function, and joint pain.

But Instaflex Advanced has some problems.

Serious problems.

The biggest issue is the underdosed hyaluronic acid. Instaflex only provides 5mg, whereas the studies showing any benefits used at least 80mg – with some using 200mg!

Other joint supplements typically contain 100mg of hyaluronic acid per serving, so Instaflex Advanced can’t really compete here.

The’re also the issue of pointless ingredients.

Collagen does nothing for joint health. Oral use of this ingredient doesn’t actually strengthen your collagen.

Resveratrol, while generally considered healthy, is not going to have a substantial effect on your joint pain or flexibility.

The bottom line is: Instaflex Advanced’s formula is not bad all all, but it’s far from the best on sale today.

If you want a supplement to ease joint pain, increase flexibility, and sustain long-term joint function, then Instaflex Advanced isn’t a terrible option.

However, there are definitely better formulas on the market to choose from. The current leading joint supplements offer better value for money overall – combining more ingredients, and using more effective ingredients, while being less expensive than Instaflex Advanced.

Side Effects – Is Instaflex Advanced Safe?

What are the side effects of using Instaflex?

Possible side effects linked to Instaflex Advanced are:

  • Nausea
  • Headaches
  • Vomiting
  • Itching
  • Constipation
  • Indigestion

Discontinue use and talk to a medical professional if you experience any of these side effects.

That being said, joint supplements are generally safe and free of side effects; the ingredients in them don’t normally cause negative reactions.

The ingredients Instaflex uses are all common in joint stacks. They have all been subjected through rigorous research, and have been shown as safe for human consumption.

When side effects have been found in research, they have been mild and rare.

Most people should be able to take Instaflex Advanced daily without experiencing any side effects at all.

However, everyone is different. We all have unique medical histories, intolerances, and so on.

It is important to do proper research before taking Instaflex, or any other joint health supplement as a matter of fact. If in doubt, always check with your doctor first.

What are Others Saying About Instaflex? Customer Reviews Analysis

Before purchasing a joint supplement like Instaflex Advanced, it’s worth checking some reviews of the product posted by other people.

While the type of Instaflex reviews you find on Amazon, GNC, and official website aren’t going to be 100% trustworthy, they can give you an overall picture of the supplement. Simply put, Instaflex Advanced reviews shared by “real people” can help you determine if it is a legitimate product, or perhaps a scam!

Here’s what some users said about Instaflex:

“I order the pills for my mom to help with her arthritis. They work great! However, I was disappointed to see that the bottle had 29 pills instead of 30. A bottle of instaflex is expensive so I didn’t expect to get shortchanged on the amount advertised in the bottle. I would’ve given this product 5 stars if the bottle contained the correct amount of pills. BEWARE and count the amount of pills in your bottle instaflex.” – Lex

“I tried these for a month for arthritis in my knee. While there may have been some easing of discomfort, it is not worth $60/month for the small amount of benefit.” – Dorothy

“I thought it was going to work magic! Not really! I’ll keep looking! Kdeekid

As we mentioned, you will need to take these testimonials with a grain of salt. Anyone can publish on eBay, Walmart, GNC, and Amazon nowadays, even if those retailers claim they can filter out fake reviews.

However, user reviews do tell us whether the product is a complete scam or not. Fortunately, in the case of Instaflex Advanced, there are no usual complaints that accompany a scam product; these include unauthorized credit card charges or aggressive billing policies.

Pricing & Value?

Instaflex Advanced costs $52.99 for a bottle of 30 capsules. Instaflex is available in Canada, Australia, and the UK. You can buy it on the official website in GNC stores, Amazon, and Walgreens pharmacies – so the price can vary depending on where you purchase it (from).

Final Thoughts on Instaflex Advanced

Instaflex is not a bad joint stack. But is it the best? We wouldn’t go that far.

It contains a few great ingredients, including some highly potent plant extracts that will definitely promote joint function and protect from general wear and tear.

Instaflex Advanced will help you with joint pain and long-term function going forward. However, there are several problems with the supplement that make it fall behind the industry-leading brands.

It contains only 5mg of hyaluronic acid, which is far below the minimum effective amount used in studies – 80-200mg.

It contains collagen, which only looks good on the label, but doesn’t actually do anything for your joints. If you want to strengthen your collagen, taking more collagen orally isn’t the way to do it!

As a whole, Instaflex Advanced is a decent product, but for the price it charges, we can’t recommend it. A large portion of its formula consists of weak ingredients. With a little research, it’s possible to find more targeted joint stacks at this Instaflex’s price range.

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