
Today we have this Instaflex vs Osteo Bi Flex comparison for you.
Joint supplements are growing in popularity each year. With it, so does the number of options on the market.
If you’re looking for the best joint supplement for flexibility, pain reduction, and everyday comfort, then you might get confused by the sheer number of options that are available. Not to mention the marketing hype of these supplement companies, which makes it hard to tell which claims are legit, and which ones are total garbage!
Today we’ll inspect two highly popular joint supplements – Instaflex and Osteo Bi-Flex – to see which one comes out on top, and how they compare to other market-leading joint health stacks.
Ready to learn more? Let’s get started with a quick summary of our report.
Instaflex vs Osteo Bi Flex Comparison Summary:
While Instaflex and Osteo Bi Flex are both decent products, they don’t quite live up to the hype that they’ve been getting online. Instaflex and Osteo Bi Flex are both natural supplements, which means they’re great alternatives for people who don’t want to go the prescription route.
Instaflex contains a high-curcuminoid turmeric powder which will help relieve your joint pain as well as lower systemic inflammation. Osteo Bi Flex, on the other hand, is better suited for promoting cartilage repair and long-term joint health with its high dose of glucosamine, Boswellia Serrata, and MSM.
However, both products have some major downsides.
Both use several ineffective and unproven ingredients that you’re paying a hefty price for. Instaflex also has some of its key ingredients underdosed. In Osteo BI Flex’s case, it doesn’t even show some of its ingredient doses, as they’re masked in a proprietary blend. However, while neither of these two supplements makes it on our “top list,” we pick Osteo Bi Flex as the better option between the two due to its significantly cheaper price.
What do we recommend?
– Click to See The Current 3 Best-Reviewed Joint Supplements-
Instaflex vs Osteo Bi Flex: Product Overview
Instaflex
Instaflex (aka, Instaflex Advanced) is one of the most popular joint supplements available today. It’s been one of the top-selling joint stacks for a while now, and doesn’t seem to be going “out of trend” anytime soon. But what does Instaflex actually do? Who is it for?
Instaflex is an all-natural anti-inflammatory supplement. It targets your joints and surrounding tissues to alleviate pain and discomfort. Additionally, Instaflex claims to help you:
- Improve flexibility
- Enhance motility
- Provide relief from joint aches in 7 days
Quite strong claims these are. Below we’ll see how they hold up when checked against the available scientific evidence.
Before that, let’s have a quick look at its competitor – Osteo Bi Flex.
Osteo Bi Flex
Osteo Bi Flex is an extremely hyped joint supplement, much like its competitor. Osteo Bi Flex has been on sale for a while now. In the US, it has been mainly sold at Walmart, CVS, Kroger, and also Amazon.
According to its manufacturers, you should experience these benefits from Osteo Bi Flex:
- Enhances joint mobility
- Relieves joint stiffness
- Soothes joint aches
Much like Insteaflex, Osteo Bi Flex also aggressively claims it can give you joint comfort within 7 days. This is really quite a bold claim. Very few supplements out there can realistically claim to work in such a short period of time. Especially joint supplements.
Normally, it will take a few weeks at least to notice significant improvements in joint pain and flexibility. This is due to the simple fact that it takes time to repair connective tissue and lower systemic inflammation, among others.
Instaflex vs Osteo Bi Flex: Comparing the Ingredients
Instaflex and Osteo Bi Flex have significantly different ingredient profiles. They only have two ingredients in common; Boswellia Serrata and hyaluronic acid.
While Instaflex’s ingredients are better at reducing inflammation, Osteo Bi Flex’s formula is more focused on promoting collagen production, cartilage repair, and long-term joint health.
Which one do we rate as more effective?
Let’s take a closer look.
Instaflex
The ingredients in Instaflex are:
- Turmeric – 200mg
- UCII (25% collagen) – 40mg
- Hyaluronic acid – 5mg
- Resveratrol – 100mg
- ApresFlex Boswellia serrata extract – 100mg
- BioPerine – 5mg
As shown on the label:

As a whole, Instaflex is a pretty solid joint formula. It consists of several ingredients that are better than those in many popular joint health pills today. But Instaflex is also far behind the leading joint formulas on the market.
As we said, you will find some great ingredients in Instaflex. We get a quality extract of the Boswellia Serrata plant, along with some turmeric and hyaluronic acid. Together, these substances will help alleviate your joint pain and strengthen your joints moving forward.
But there are also some major drawbacks.
The biggest one is the low dose of hyaluronic acid. At only 5mg per serving, we’re getting far below the minimum optimal dosage of 80mg. Some studies used 200mg or more.
It’s unrealistic to be expecting any beneficial effects from 5mg of hyaluronic acid. This dose is far too weak to produce changes in your joint pain, function, or overall joint health.
Another problem with Instaflex Advanced is that it contains several ineffective ingredients. In fact, a significant portion of Instaflex consists of Resveratrol and Collagen, two ingredients that won’t to anything for your joint health.
Oral collagen doesn’t work. Consuming more collagen doesn’t actually strengthen your collagen, despite the marketing hype around it. It doesn’t matter which type of collagen you’re using in supplements – chicken collagen, type II collagen, or any other form – it hasn’t been shown to work!
Unless you’re consuming 10s of grams of collagen through supplements, don’t expect it to be doing anything, as it’s poorly absorbed by the body. Obviously, Instaflex doesn’t have nowhere near the amount of collagen required to have any effect at all.
As for resveratrol, it has general health benefits, but it won’t give you a noticeable benefit in terms of joint pain or flexibility.
So with all things considered, do we think Instaflex’s formula is good? Sure. It’s definitely better than many other joint stacks out there. But is it the best? That’s a resounding no!
The more relevant question, however, is: is Instaflex better than Osteo Bi Flex?
Osteo Bi Flex
Osteo Bi Flex Triple Strength ingredients are by far the most important aspect of this supplement. They will tell us whether Osteo Bi Flex is any good for promoting what it claims to promote, and how it compares to its fierce competitor – Instaflex.
Here are the ingredients you’ll find in the Osteo Bi-Flex:
- Glucosamine HCl (1500mg)
- Chondroitin/MSM Complex (1103mg)
- Joint Shield 5-LOXIN ADVANCED (Boswellia serrata extract) (100mg)
- Chondroitin sulfate (unknown dose)
- MSM (unknown dose)
- Collagen (unknown dose)
- Boswellia serrata (unknown dose)
- Boron (unknown dose)
- Hyaluronic acid (unknown dose)
As shown on the label:

Osteo Bi Flex is not a bad joint supplement, at all. It’s certainly not a scam, and many of its positive reviews online aren’t too far off.
Compared to Instaflex, Osteo Bi Flex contains a few unique ingredients that make it stand out. But it also contains some pointless and unproven ingredients – much like Instafle does.
In other words, Osteo Bi Flex does have some advantages over Instaflex in terms of the formula, but it also falls behind its competitor in certain areas. So both products have their pros and cons.
This leaves us with a similar conclusion about Osteo Bi Flex’s ingredients as with Instaflex’s: it’s a good joint supplement, but it’s not the best. Not even close.
Glucosamine in Osteo Bi Flex is an excellent ingredient choice. It’s been shown to be highly effective for enhancing cartilage strength and density, promoting long-term joint health.
Boswellia serrata that is found in the formula is also a highly effective joint/bone health enhancer. Numerous studies show that a quality Boswellia Serrata Extract (such as 5-LOXIN Advanced) can reduce joint pain. In some studies, joint health improved in about a week (which is where Osteo Bi Flex might be getting its “joint health improvements within 7 days” claim from).
However, Osteo Bi Flex is not without problems. Some of its ingredients are absolutely useless for a joint supplement.
Collagen is ineffective when taken orally; it passes through your stomach mostly undigested and unabsorbed by the body.
Hyaluronic acid is a common ingredient in cosmetics, and is sometimes used for promoting joint health. Although human studies on hyaluronic acid are still not conclusive, we don’t know the dosage that Osteo Bi-Flex is using, as the ingredient is hidden in a proprietary blend.
Boron is a mineral which doesn’t have any known deficiency symptoms; and it certainly doesn’t have an effect on joint health based on the current evidence. Plus, we already get enough of this trace mineral through apples, dried fruits, and many other foods.
As a whole then, Osteo Bi Flex is sort of a mixed bag joint stack. On the positive note, Osteo Bi Flex contains generous dosages of some effective, clinically-supported ingredients. But a large chunk of the formula also appears to contain a lot of pointless junk that you’re paying for. The most problematic of all, we can’t even see the doses of some ingredients!
Our Commentary on Instaflex vs Osteo Bi-Flex Ingredients
As we’ve seen, both Instaflex nor Osteo Bi-Flex have decent ingredient profiles – a lot better than the masses of joint health supplements out there. Still, they both have some major downsides that makes us hesitant to recommend them over the current market-leading joint stacks.
If we had to choose between the two, though, which has the better formula? In our opinion, Osteo Bi Flex is better. It contains higher amounts of glucosamine, chondroitin, and MSM – key ingredients that help to support your long-term joint function and strength, as well as promote cartilage repair.
On the other hand, Instaflex’s advantage is that it contains turmeric – which is a potent anti-inflammatory. As such, Instaflex is more effective at alleviating pain in the short-term, but as a long-term solution, we rate Osteo Bi-Flex as the better option.
Instaflex vs Osteo Bi Flex: Safety Analysis
Both Instaflex and Osteo Bi Fle are safe, natural dietary supplements. The answer to if they will cause side effects is “probably not.”
The ingredients in both supplements have all been tested for safety in robust clinical studies, on human volunteers, and have been found to healthy for normal consumption.
The ingredients in Osteo Bi-Flex and Instaflex are all common in joint supplements (for better or worse). Joint supplements in general, and especially the very best joint supplements, are not known to cause serious side effects.
That said, there’s a caveat in that we don’t know the individual doses of some key ingredients in Osteo Bi Flex. The Glucosamine in this supplement is dosed extremely high. Muhc more than the typical 300-500mg found in most good-quality joint products.
As a result, side effects are always a possibility. If you experience any, you should stop using the product and contact your doctor.
Instaflex vs Osteo Bi Flex: User Reviews
Generally, Instaflex and Osteo Bi-Flex both boast mostly positive customer reviews. Out of the thousands that are shared online, many of them say good things about the benefits of both of these joint supplements. You will occasionally stumble across a negative review saying how the effects weren’t as good as they wanted. There are also reports of mild negative side effects, albeit rare.
It’s a good idea to take online testimonials with a pinch of salt, as it’s difficult to tell which ones are legitimate, and which are not. It’s quite easy nowadays to write fake negative, or positive testimonials about the product, despite the claims of Amazon and other big retailers that they filter out the fake reviews.
With that being said, looking at product testimonials online can give you a good general idea about the product. Above all, the user reviews will almost always tell you if the product in question is legitimate, or a total scam! The latter doesn’t appear to be the case with Instaflex nor Osteo Bi-Flex.
Instaflex vs Osteo Bi Flex: Pricing & Value
Instaflex costs between $52.99 per. bottle. Each bottle lasts you a month.
As for Osteo Bi Flex, the price can vary depending on the version you choose, as well as where you buy it. A 120-capsule bottle of Osteo Bi Flex costs $34.89 on iHerb. On Amazon the price can climb up to $42.99. So again, do your research if you’re planning to buy this supplement, to ensure you get the most bang for your buck.
The Bottom Line
That concludes our Instaflex vs Osteo Bi Flex comparison. In terms of pricing, Osteo Bi Flex definitely takes the edge as the cheaper option.
Instaflex, on the other hand, takes a lead in terms of popularity and customer reviews online.
From our analysis, Instaflex is more effective at relieving short-term joint pain, but it’s not as good as Osteo Bi-Flex in terms of promoting cartilage repair and supporting long-term joint health.
That being said, both Instaflex and Osteo Bi-Flex have some major downsides. Both use unproven ingredients, including collagen, which is ineffective when taken orally. Instaflex also has a few of its key ingredients underdosed. With Osteo Bi Flex, we are not even able to see the doses of some ingredients, as they’re hidden behind a proprietary blend.
At the end of the day, we think there are better options than either of these two products. Needles to say, marketing hype doesn’t always equal an effective product! For the price that’s being charged, you can find more transparent, more comprehensive, and better-dosed joint stacks on the market, without a doubt.
Not what you were looking for?
– Click to See The Current 3 Best-Reviewed Joint Supplements-
Further Reading:
i have them both so fat i have been using one oday ony now i am waiting for some results i habeen taking bi-flex about a week so fat very ittle improvement in hip movemen just gotta wait and see still in the early stages yet