
Today we’ve got a face-off between Relief Factor and KaraMD Comfort Guard X24 – two natural, popular joint health supplements that you can buy online.
In this Relief Factor vs Comfort Guard comparison, we’ll see which one is better at reducing your joint pain, improving flexibility, and managing chronic inflammation among others. To determine the winner, we’ll be inspecting their ingredients and seeing if the science agrees with the manufacturers’ claims.
Short on time? Let’s start with a brief summary.
Relief Factor vs Comfort Guard Summary
While neither Comfort Guard nor Relief Factor makes it on the list of the best joint supplements, Comfort Guard is the clear winner of this comparison.
It has better-quality ingredients than Relief Factor, including a high-curcuminoid turmeric extract. Relief Factor uses plain turmeric powder which you can cheaply buy at your local supermarket, and the other half of its formula consists of ineffective or unproven ingredients.
That said, Comfort Guard is far from the best joint stack around. Some of its key ingredients are underdosed, and it doesn’t have BioPerine (black pepper extract) to improve turmeric’s poor absorption. As a result, we don’t recommend either of these two as the very best supplements for joint health. There are better options on sale today, no doubt about it.
What do we recommend?
– Click to See The Current 3 Best-Reviewed Joint Supplements-
Comfort Guard vs Relief Factor: Product Overview
Comfort Guard
KaraMD Comfort Guard X24 is a “doctor-formulated” inflammation, joint and pain management supplement for both men and women. All-natural, non-GMO, and vegan-friendly, Comfort Guard contains ingredients like turmeric, Boswellia, and Ginger, which are claimed to target inflammation in your joints to improve your joint function and comfort.
KaraMD is a company based in Cleveland, Ohio. They have many offerings in their supplement range – including fat burners, greens supplements, and sleep aids. But their arguably most popular supplement right now it Comfort Guard, which is said to improve your joint function and relieve pain.
But does KaraMD Comfort Guard X24 really work? Is this an over-hyped supplement, or is it actually backed by evidence? Are the ingredients safe? How does it compare against Relief Factor in terms of effectiveness, safety, and value for money? Make sure to read on as we cover all of these questions in following sections.
Relief Factor
When it comes to joint supplements, Relief Factor is even more popular than its competitor, KaraMD Comfort Guard. In fact, Relief Factor might very well be the most hyped joint stack on the market right now. It has hundreds of reviews online, many of them praising the awesome benefits and ingredients of this product.
But what does it actually do?
According to its makers, Relief Factor can give you:
- Anti-inflammatory response
- Less pain in hips, knees, ankles, and joints in general
- Strengthens long-term joint function
The benefits listed are something you’d expect from any good-quality joint supplement. Obviously, Relief Factor is a stack formulated to reduce joint pain caused by inflammation and wear and tear of your connective tissues.
There isn’t a lot of talk about improving joint mobility or flexibility. There’s nothing on the Relief Factor website that would suggest that this product can help repair your cartilage and connective tissues. The only benefit we’re promised is a reduction in joint pain and long-term discomfort.
That naturally brings up the question: is Relief Factor the right product for you? And how does it compare to Comfort Guard in terms of effectiveness?
We investigate their ingredients to find out.
Relief Factor vs Comfort Guard: Comparing the Ingredients
Relief Factor Ingredients
The active ingredients of Relief Factor are:
- EPA – 647mg
- DHA – 253mg
- Turmeric (18% curcuminoids) – 667mg
- Epimedium (20% Icariin) – 200mg
- Japanese fleeceflower (96% resveratrol) – 70mg
Here’s a closer look at the label:

On the whole, Relief Factor looks like a decent formula. It has a few well-researched ingredients like turmeric and omega-3 oils which can help manage your joint inflammation and pain. But is Relief Factor the best joint stack you can find? Far from it!
The formula has some major issues that need to be addressed.
To start with, Relief Factor uses a number of unproven, ineffective ingredients. These include Japanese fleeceflower (knotweed) and Epimedium.
Japanese fleeceflower has never been used in quality joint supplements. In fact, we’ve never seen it being used in any high-quality supplement at all. This ingredient has no evidence to support its use for joint pain or flexibility. There’s absolutely nothing that would make us think this stuff can benefit us in any way.
Epimedium, on the other hand, is indeed effective, but not for joint health. Epimedium is also known as “Horny Goat Weed,” so you can guess what is it used for.
You’ve guessed it – Epimedium is a libido-enhancing supplement. We have no idea what it is doing in Relief Factor. There’s certainly no evidence to support its use for joint health.
A concerningly large part of Relief Factor is basically useless, ineffective ingredients.
But as we mentioned, it does have a few ingredients that are solid.
Turmeric and omega-3 oils are generally seen and healthy. They have anti-inflammatory effects, which can reduce your joint pain, especially if it’s caused by things like osteoarthritis.
However, here’s the issue. For such an expensive supplement, Relief Factor is using a standard turmeric powder. The same one you can buy from your local grocery shop.
Needless to say, this form of turmeric has poor absorption. The best supplements typically pair turmeric with piperine (black pepper extract) to drastically increase the bioavailability of curcuminoids (active compounds of turmeric), but Relief Factor doesn’t have that either.
As for omega-3s, Relief Factor contains only 900mg per serving. Compare this to the expert recommended dosage of 2,000mg or more, and it’s clear Relief Factor won’t give you the full effect from its ingredients.
So even where there are good ingredients, there are still problems.
While this formula is not terrible, or the worst one we’ve seen, it has a lot of room for improvement! This is not really acceptable when the price of the product is over $90. More on this below.
For now, let’s look at what Comfort Guard has to offer. Is the formula better than Relief Factors?
Comfort Guard Ingredients
Comfort Guard ingredients are:
- Turmeric Root Powder – 1050mg
- Boswellia Serrata Extract 200mg
- Turmeric 95% Root Extract 150mg
- Ginger 100mg

Unlike Relief Factor, Comfort Guard does use high-quality forms of ingredients.
This includes the high-curcuminoid turmeric extract. Comfort Guard also contains some ginger and Boswellia Serrata, both of which are excellent joint health ingredients.
Ginger is an excellent complement to turmeric, as it further reduces inflammation and pain in joints. Boswellia Serrata, on the other hand, blocks enzymes in your body that cause pain and the destruction of joint tissues.
On the whole, we’re happy to see that Comfort Guard doesn’t waste too much capsule space on pointless ingredients, unlike its competitor.
But even though Comfort Guard has better ingredients than Relief Factor, it is also far behind the market-leading joint supplements in terms of quality.
There are a couple of serious issues with Comfort Guard that makes us hesitant to recommend it to anyone serious about improving their joint health.
One is that Comfort Guard’s key ingredients are underdosed. There’s only 200mg of Boswellia Serrata in the product, whereas studies show the minimum effective dose is around 300-500mg; ideally, taken multiple times per day.
Ginger’s dose is below optimal, as well. Comfort Guard only has 100mg of ginger, compared to the very best joint stacks on the market which use more than double – 250mg per serving.
There’s also the issue of missing ingredients. Comfort Guard, as good as some of its ingredients are, is missing quite a lot from its formula to be called one of the very finest joint stacks on sale right now. There’s no selenium, no MSM, nor there is any Glucosamine or Chondroitin to support the repair of joints and connective tissues.
The bottom line is: Neither Relief Factor nor Comfort Guard has the best joint health formula we’ve seen. Although Comfort Guard is likely to give you better pain relief than Relief Factor, it’s still a lot weaker than some other options on the market. The formula of Comfort Guard is incomplete, and its key ingredients are underdosed.
Relief Factor vs Comfort Guard: Safety Analysis
Both Relief Factor and Comfort Guard are safe supplements. They’re naturally sourced, free of harmful substances, and their active ingredients haven’t been shown through scientific research to cause negative reactions.
Will you get side effects from either of these two? The answer is highly unlikely.
However, if you have a condition, or if you are not sure if Relief Factor or Comfort Guard are right for you, check with your doctor before using either one.
Relief Factor vs Comfort Guard: User Reviews
Comfort Guard vs Relief Factor, which is the customer’s favorite? The truth is, both are highly popular online, with hundreds of reviews on websites like Amazon. While reading testimonials from “real people” can give you a general idea about the product, it can be difficult to filter out through fake reviews and paid ads.
Although Amazon and other big retailers claim they only show real reviews, that’s not really the case. Anyone who’s at least a little tech savvy can log into Amazon nowadays and write a review. Therefore, it isn’t too hard for these companies to pay hundreds if not thousands of people to write positive reviews about the products.
The same is true for negative reviews. The competitors of these products can pay users, or even use robots, to write fake, negative testimonials.
That being said, we still think it’s worth reading other reviews online as this will give you an idea if you’re dealing with a legitimate supplement or a total scam! The latter doesn’t appear to be the case with either product.
Relief Factor vs Comfort Guard: Pricing & Value
Relief Factor will cost you $93.05 for a month’s supply, in addition to shipping and handling.
If you’re buying it for the first time, the manufacturers offer Relief Factor for $19.95. However, there’s a good reason why it’s so “cheap”. If you opt for this first-time purchase price, you will be automatically subscribed to regular shipments of Relief Factor. This means you will be recurringly charged for Relief Factro from the moment you purchase it for the first time.
Two weeks after you initial order, Relief Factor will charge you an additional $99.95 for a 2-month’s worth supply of Relief Factor. This will be a recurring payment plan.
Worst of all, Relief Factor doesn’t come with a money-back guarantee. If you’re not happy with the results from the product, well, there’s not a lot you can do! What you can do is return the unused product within 30 days of making your purchase – if you do this, you will get your money back, according to the manufacturer.
Comfort Guard’s pricing structure is a lot less complicated. A 30-serving bottle of Comfort Guard will cost you $29.95 on Amazon, though the price can vary depending on where you buy it from. KaraMD Comfort Guard offers a 90-day money-back guarantee.
Needless to say, in the “value for money” department, Comfort Guard takes a clear lead. Even though it’s far from the best joint supplement out there, it’s still significantly cheaper, and doesn’t automatically charge your credit card like Relief Factor.
The Bottom Line
Which is better, KaraMD Comfort Guard X24 or Relief Factor?
The answer is that Comfort Guard is the better value for money overall. Comfort Guard likely will have more of an effect than Relief Factor, while Relief Factor costs a small fortune but uses underdosed and ineffective ingredients.
That said, neither of these supplements make it on our “top list” of the very best joint stacks.
If you’re serious about reducing joint pain and maximizing joint function in the long run, then neither Comfort Guard nor Relief Factor is the best option. Instead, a pharmaceutical-grade joint formula developed by professionals is the best way to ensure pain-free, long-lasting joint function with minimal risk of side effects and maximum efficacy.
What do we recommend?
– Click to See The Current 3 Best-Reviewed Joint Supplements-
Related:
Leave a Reply